4.3.0 CTD

Responding again to my own post, I did a complete, fresh reinstall of Cemu 1.15.8, Cemu Hook .572, and ReShade 4.3.0.
CTD on specific game (XCX or BOTW) launch.
I read through the ReShade forums, but nothing in particular jumped out at me.
I disabled on-screen overlays from both GeForce Experience (wasn't activated) and Steam (was, then disabled).
No help.
So installed ReShade to another game I have--Dragon Age Inquisition.
Bingo!
DAI also crashes on launch. reshade.me states ReShade works "perfectly" for DAI. Probably it does, but not 4.3.0. CTD.
FYSA.
Cross-posted to reddit.com/r/cemu forum.

Just quickly, are you on a laptop with integrated (i.e, Intel) and dedicated (i.e AMD or Nvidia) graphics?

Yes. Intel 630 and GTX1080.
Are we hitting on something with this observation?
Maybe I'm doing something dumb.

Yep there's a known issue with laptops and hybrid graphics. I don't know the specifics, but the result is a crash as you describe. Crosire may me able to explain better, but I think it's related to having multiple graphic driver stacks interfering with how Reshade hooks them for a game.

The solution is to disable the Intel GPU (presumably in the BIOS).

Thanks!

Yep. That was it exactly.I guess no way to force Reshade through the ini or similar to hook to a particular card. Ah well.
Anyway, ReShade works now (no BIOS setting; disabled in Device Manager). Thanks!