I'm having the same issue and it's related to DLSS apparently.
Cyberpunk + Linux + DLSS (no Reshade) -> 100% Stable
Cyberpunk + Linux + Reshade (no DLSS) -> 100% Stable
Cyberpunk + Linux + DLSS + Reshade -> crash after 1-10 mins of gameplay
I've tried the nightly Reshade builds (including the recent one that fixed DLSS black screen issues, and later ones up to a2ab290 from today) to no avail. I've tried several different proton-cachyos versions (which are based on very recent proton builds, up to
10.0-20260420
), both with & without the new heap descriptor branch, and in that branch both with & without heap descriptor support enabled, but the problem is always the same.
There's nothing in the Reshade logs related to the crash, but I'm happy to provide them. Here is a slightly older Reshade nightly + proton log, but I can provide a newer one if you want too.
www.dropbox.com/scl/fi/ukkzg7l9px5ks1fdo...9cl&st=bpj3gljx&dl=0