I used Resade since a year whith WoW. With the release of patch 8.1 i deinstalled Reshade and installed the latest version of Reshade in the new folder of WoW and it works until yesterday. Today i started WoW and Reshade does not work. I have uninstalled and installed it again but it still does not work.
I know why yours isn't working. They switched the wow default settings to "DX12" and reshade doesn't work with DX12. So you just have to go to settings and switch it back to DX 11. If that doesnt work, make sure you installed reshade to the "Retail" folder!
The following user(s) said Thank You: Silverseppel